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Are side effects permanent from fillers and hylanex?

Cosmetic Treatments QuestionsCategory: HyaluronidaseAre side effects permanent from fillers and hylanex?
A patient asked 4 years ago
I had fillers done in October and I felt the dr. used too much so I started to have it dissolved with hylanex by another dr. Although it was all dissolved my face looks different than it did before fillers. The lines around my mouth are much wider than they used to be and I have a permanent “new” line above my folds on o e side. I am so upset about this. Lots of regrets! Will I ever look like myself again?
1 Answers
Dr. Elham Jafari Staff answered 4 years ago

Lasting Effects of Filler and Hylenex

Hi and thank you for your question! As you know, hyaluronic acid is naturally present in our skin and is the primary component of the extra cellular matrix responsible for retaining water in the skin. When we inject hyaluronidase (Hylenex) to dissolve filler, it might also act on naturally present hyaluronic acid in the skin and dissolve part of that as well. This being said, the natural hyaluronic acid in our skin is not constant and it also undergoes remodeling all the time with new hyaluronic acid made and old molecules degraded. As we age, this remodeling slows down with a net negative effect on overall volume on our face. However in your case, since the filler and enzyme treatments were so recent, I won’t be worried much and the I recommend that you allow more time for your skin to reach a balance. At that time, we can always do some new filler injections to correct any remaining issues. I hope it helps and good luck!


IMPORTANT: These answers are for educational purposes only and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.
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