Hi and thank you for your question! Some patients do develop “tolerance” to Botox and other medications in the group which is associated with reduced effectiveness. While Botox (and Dysport or Xeomin) address different issues versus fillers such as Restylane, in your case when the frown lines are too deep, it is possible to smooth them out to some extent with filler injection. For this area, I suggest using fillers that absorb less water once injected to avoid compromising the local blood flow given the proximity to superficial arteries. I hope it helps and good luck!
Please login or Register to submit your answer